Fifth Third Bank is a large U.S. regional bank and financial services company headquartered in Cincinnati, Ohio, operating under its parent Fifth Third Bancorp. Founded in 1858, the bank provides a broad suite of services across commercial banking, consumer lending, wealth and asset management, and capital markets, serving individuals, corporations, and institutions across the Midwest and Southeast. It is one of the largest regional banks in the U.S., with over $200 billion in assets and more than 1,000 branches, and has recently expanded its scale further through acquisitions, including its 2026 merger with Comerica to become one of the top 10 U.S. banks by assets.
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